Our lab studies environmentally-switched protein/protein interaction domains about their natural regulation and understand how to artificially control them in vitro and in living cells. This is exemplified by our work on photosensors, parts of the hypoxia response, and others.

Oct 2014: The lab moved to New York City last month, establishing the Structural Biology Initiative of the CUNY Advanced Science Research Center. Kevin directs this new initiative, which will catalyze collaborations among biological and physical scientists in the CUNY system. Kevin has also joined the CCNY Dept. of Chemistry as part of this move.

Please note the new URL (kglab.org) for this site, which will update with new contact info, and find me by email with any questions or comments - Kevin Gardner, Oct 2014

for October 31, 2014, as found in VP Denisov et al., Nat. Struct. Biol. 3(1996): 505:

"While the Arrhenius equation is still widely used to analyse temperature dependent protein conformational dynamics, the two-state picture on which it rests can hardly do justice to the complex topography of the energy landscape of a protein, even on a local scale."